Lois lives at 31 Spooner Street with her family and also Brian , the anthropomorphic family dog. Lois is voiced by Alex Borstein. At the time series creator Seth MacFarlane approached her for a role on the show, she was doing a live stage show in Los Angeles, playing a redhead mother in a sketch. The voice style was modeled after one of her cousins' voice. Born Lois Pewterschmidt, she was brought up in an extremely wealthy household with her sister, Carol. They also have a long-lost older brother, Patrick , who was sent to a mental asylum after he became a serial killer.
It originally aired on Fox in the United States on November 19, In this episode, Lois discovers that Chris' school has removed the sex education program due to budget cuts and decides to bring the class back by becoming the teacher. Unfortunately, she gets fired a short time later for teaching the students about safe sex rather than abstinence.
She starts working on a phone sex line, and ends up with Peter as a client. Chris builds a birdhouse he built based on an episode of Benson and Peter becomes interested in attracting birds. Chris wants the birds to reenact the Benson episode "Conflict of Interest.